Nanostructured lipid carrier for bioavailability enhancement

  • Kamaldeep Kaur Himachal Institute of Pharmacy, Paonta sahib, HP., India
  • Ujjwal Nautiyal Himachal Institute of Pharmacy, Paonta sahib, HP., India
  • Devendra Singh Tirupati life science, Paonta Sahib, HP, India.
Keywords: Bioavailability, Biocompatible, Oral route, Colloidal carriers, Toxicity


Nanostructred lipid carrier(NLC) is second generation drug carrier system having solid matrix at room temperature. This carrier  system  is  made  up  of  physiological,  biodegradable  and  biocompatible  lipid  materials  and  surfactants  and  is accepted by regulatory authorities for application in different drug delivery system. The main objective of this review is to explore the role of NLCs system for delivering drugs by oral route and thus increasing the oral bioavailability methods. The present review article highlights the definition and types of NLCs and their importance as colloidal carriers including the production techniques and their  formulation. This review article also deals with  the fate of  lipids used in the NLCs formulation and the NLCs toxicity.