FLOATING TABLET: A REVIEW

  • Naveen Sharma Himachal Institute of Pharmacy, Paonta Sahib, Distt- Sirmour, Himachal Pradesh, India.
  • Satinder Kakkar Himachal Institute of Pharmacy, Paonta Sahib, Distt- Sirmour, Himachal Pradesh, India
Keywords: Bioavailability, Gatric emptying, Interdigestive, Motility, Fundus, Myloelectric, Antrum

Abstract

The design of floating drug delivery Systems (FDDS) should be primarily aimed to achieve more predictable and increased  bioavailability.  Now-a-days  most  of  the  pharmaceutical  scientist  is  involved  in  developing  the  ideal FDDS. This ideal system should have advantage of single dose for the whole duration of treatment and it should deliver the active drug directly at the specific site. Gastric emptying occurs during fasting as well as fed states. The pattern of motility is however distinct in the 2 states. During the fasting state  an interdigestive series of electrical events  take  anatomically  the  stomach  is  divided  into  3  regions:  fundus,  body,  and  antrum  (pylorus).  The  place, which cycle both through stomach and intestine every 2 to 3 hours.14 This is called the interdigestive myloelectric cycle or migrating myloelectric cycle (MMC),

Published
2015-09-30